3kc0

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Template:STRUCTURE 3kc0

Crystal structure of human liver FBPase in complex with tricyclic inhibitor 10b

Template:ABSTRACT PUBMED 20045638

About this Structure

3KC0 is a 4 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Tsukada T, Takahashi M, Takemoto T, Kanno O, Yamane T, Kawamura S, Nishi T. Structure-based drug design of tricyclic 8H-indeno[1,2-d][1,3]thiazoles as potent FBPase inhibitors. Bioorg Med Chem Lett. 2010 Feb 1;20(3):1004-7. Epub 2009 Dec 21. PMID:20045638 doi:10.1016/j.bmcl.2009.12.056

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