This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3k9x
From Proteopedia
X-ray crystal structure of human fxa in complex with (S)-N-((2-METHYLBENZOFURAN-5-YLAMINO)(2-OXO-1-(2-OXO-2- (PYRROLIDIN-1-YL)ETHYL)AZEPAN-3- YLAMINO)METHYLENE)NICOTINAMIDE
Template:ABSTRACT PUBMED 19896847
About this Structure
3K9X is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Shi Y, Li C, O'Connor SP, Zhang J, Shi M, Bisaha SN, Wang Y, Sitkoff D, Pudzianowski AT, Huang C, Klei HE, Kish K, Yanchunas J Jr, Liu EC, Hartl KS, Seiler SM, Steinbacher TE, Schumacher WA, Atwal KS, Stein PD. Aroylguanidine-based factor Xa inhibitors: the discovery of BMS-344577. Bioorg Med Chem Lett. 2009 Dec 15;19(24):6882-9. Epub 2009 Oct 23. PMID:19896847 doi:10.1016/j.bmcl.2009.10.084
Page seeded by OCA on Wed Dec 16 13:09:13 2009
Categories: Coagulation factor Xa | Homo sapiens | Ghosh, K. | Kish, K. | Klei, H E. | Rushith, A. | Blood clotting | Blood coagulation | Blood coagulation factor | Calcium | Cleavage on pair of basic residue | Disulfide bond | Egf-like domain | Epidermal growth factor like domain | Gamma-carboxyglutamic acid | Glycoprotein | Hydrolase | Hydroxylation | Polymorphism | Protease | Secreted | Serine protease | Zymogen
