1qys

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Template:STRUCTURE 1qys

Crystal structure of Top7: A computationally designed protein with a novel fold

Template:ABSTRACT PUBMED 14631033

About this Structure

1qys is a 1 chain structure with sequence from Computationally designed sequence. The October 2005 RCSB PDB Molecule of the Month feature on Designer Proteins by David S. Goodsell is 10.2210/rcsb_pdb/mom_2005_10. Full crystallographic information is available from OCA.

Reference

• Kuhlman B, Dantas G, Ireton GC, Varani G, Stoddard BL, Baker D. Design of a novel globular protein fold with atomic-level accuracy. Science. 2003 Nov 21;302(5649):1364-8. PMID:14631033 doi:10.1126/science.1089427
• Stordeur C, Dalluge R, Birkenmeier O, Wienk H, Rudolph R, Lange C, Lucke C. The NMR solution structure of the artificial protein M7 matches the computationally designed model. Proteins. 2008 Aug 15;72(3):1104-7. PMID:18498106 doi:10.1002/prot.22107