1fkn

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spinqualitylabelsall models PDB ID 1fkn Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image
1fkn, resolution 1.90Å ()
Non-Standard Residues:
Activity:	Memapsin 2, with EC number 3.4.23.46
Structural annotation: Resources: CATH : 1Fkna01, 1Fkna02, 1Fknb02, 1Fknb01 InterPro : Ipr009007, Ipr001461, Ipr009119, Ipr009120, Ipr001969 Pfam : PF00026 SCOP : d1fkna_, d1fknb_ UniProt : P56817
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, PDBsum, RCSB
Coordinates:	save as pdb, mmCIF, xml

Contents 1 Structure of Beta-Secretase Complexed with Inhibitor 2 About this Structure 3 See Also 4 Reference

Structure of Beta-Secretase Complexed with Inhibitor

Template:ABSTRACT PUBMED 11021803

About this Structure

1fkn is a 4 chain structure of Beta secretase with sequence from Homo sapiens. The July 2006 RCSB PDB Molecule of the Month feature on Amyloid-beta Precursor Protein by David S. Goodsell is 10.2210/rcsb_pdb/mom_2006_7. The July 2009 RCSB PDB Molecule of the Month feature on beta-Secretase by David Goodsell is 10.2210/rcsb_pdb/mom_2009_7. Full crystallographic information is available from OCA.

See Also

• Beta secretase

Reference

• Hong L, Koelsch G, Lin X, Wu S, Terzyan S, Ghosh AK, Zhang XC, Tang J. Structure of the protease domain of memapsin 2 (beta-secretase) complexed with inhibitor. Science. 2000 Oct 6;290(5489):150-3. PMID:11021803