3hg4

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Image:3hg4.png

Template:STRUCTURE 3hg4

Contents

Human alpha-galactosidase catalytic mechanism 3. Covalent intermediate

Template:ABSTRACT PUBMED 19940122

Disease

Known disease associated with this structure: Fabry disease OMIM:[300644], Fabry disease, cardiac variant OMIM:[300644]

About this Structure

3HG4 is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Guce AI, Clark NE, Salgado EN, Ivanen DR, Kulminskaya AA, Brumer H 3rd, Garman SC. Catalytic mechanism of human alpha-galactosidase. J Biol Chem. 2010 Feb 5;285(6):3625-32. Epub 2009 Nov 25. PMID:19940122 doi:10.1074/jbc.M109.060145

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