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2x23

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Image:2x23.jpg

Template:STRUCTURE 2x23

CRYSTAL STRUCTURE OF M. TUBERCULOSIS INHA INHIBITED BY PT70

Template:ABSTRACT PUBMED 14623976

About this Structure

2X23 is a 4 chains structure with sequences from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

Reference

  • Rawat R, Whitty A, Tonge PJ. The isoniazid-NAD adduct is a slow, tight-binding inhibitor of InhA, the Mycobacterium tuberculosis enoyl reductase: adduct affinity and drug resistance. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):13881-6. Epub 2003 Nov 17. PMID:14623976 doi:10.1073/pnas.2235848100

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