2x8h

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Image:2x8h.jpg

Template:STRUCTURE 2x8h

MAPPING THE CATALYTIC CYCLE OF SCHISTOSOMA MANSONI THIOREDOXIN GLUTATHIONE REDUCTASE BY X-RAY CRYSTALLOGRAPHY

About this Structure

2X8H is a 1 chain structure with sequence from Schistosoma mansoni. Full crystallographic information is available from OCA.

Reference

  • Angelucci F, Miele AE, Boumis G, Dimastrogiovanni D, Brunori M, Bellelli A. Glutathione reductase and thioredoxin reductase at the crossroad: the structure of Schistosoma mansoni thioredoxin glutathione reductase. Proteins. 2008 Aug 15;72(3):936-45. PMID:18300227 doi:10.1002/prot.21986
  • Angelucci F, Sayed AA, Williams DL, Boumis G, Brunori M, Dimastrogiovanni D, Miele AE, Pauly F, Bellelli A. Inhibition of Schistosoma mansoni thioredoxin-glutathione reductase by auranofin: structural and kinetic aspects. J Biol Chem. 2009 Oct 16;284(42):28977-85. Epub 2009 Aug 26. PMID:19710012 doi:10.1074/jbc.M109.020701

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