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3jub
From Proteopedia
Contents |
Human gamma-glutamylamine cyclotransferase
Template:ABSTRACT PUBMED 20110353
Function
[A2LD1_HUMAN] Contributes to degradation of proteins cross-linked by transglutaminases. Degrades the cross-link between a lysine and a glutamic acid residue from two proteins that have been cross-linked by transglutaminases. Catalyzes the formation of 5-oxoproline from L-gamma-glutamyl-L-epsilon-lysine. Inactive with L-gamma-glutamyl-alpha-amino acid substrates such as L-gamma-glutamyl-L-alpha-cysteine and L-gamma-glutamyl-L-alpha-alanine.
About this Structure
3jub is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Oakley AJ, Coggan M, Board PG. Identification and characterization of gamma-glutamylamine cyclotransferase, an enzyme responsible for gamma-glutamyl-epsilon-lysine catabolism. J Biol Chem. 2010 Mar 26;285(13):9642-8. Epub 2010 Jan 28. PMID:20110353 doi:10.1074/jbc.M109.082099
