Ketosteroid Isomerase

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Introduction

Ketosteroid Isomerase (KSI; PDB 1ISK)

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Ketosteroid Isomerase (KSI, EC#5.3.3.1) is an enzyme that catalyzes the isomerization of 3-oxo-Δ5 ketosteroids to their hormonally active Δ4-conjugated isomers. This reaction is essential in the metabolic pathways of

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Laura M. Haynes, Michal Harel, Joel L. Sussman, Alexander Berchansky

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