3lqa

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Image:3lqa.png

Template:STRUCTURE 3lqa

Contents

Crystal structure of clade C gp120 in complex with sCD4 and 21c Fab

Template:ABSTRACT PUBMED 20357769

Disease

Known disease associated with this structure: CD4 lymphocyte deficiency OMIM:[186940], Lupus erythematosus, susceptibility to OMIM:[186940]

About this Structure

3LQA is a 4 chains structure with sequences from Homo sapiens and Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  • Diskin R, Marcovecchio PM, Bjorkman PJ. Structure of a clade C HIV-1 gp120 bound to CD4 and CD4-induced antibody reveals anti-CD4 polyreactivity. Nat Struct Mol Biol. 2010 May;17(5):608-13. Epub 2010 Mar 31. PMID:20357769 doi:10.1038/nsmb.1796

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