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3mbl

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Image:3mbl.jpg

Template:STRUCTURE 3mbl

Crystal Structure of the human mitogen-activated protein kinase kinase 1 (MEK 1) in complex with ligand and MgADP

Template:ABSTRACT PUBMED 20621728

About this Structure

3MBL is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Wallace MB, Adams ME, Kanouni T, Mol CD, Dougan DR, Feher VA, O'Connell SM, Shi L, Halkowycz P, Dong Q. Structure-based design and synthesis of pyrrole derivatives as MEK inhibitors. Bioorg Med Chem Lett. 2010 Jul 15;20(14):4156-8. Epub 2010 May 20. PMID:20621728 doi:10.1016/j.bmcl.2010.05.058

Page seeded by OCA on Wed Jul 28 12:38:19 2010

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