3h3b

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Template:STRUCTURE 3h3b

Crystal structure of the single-chain Fv (scFv) fragment of an anti-ErbB2 antibody chA21 in complex with residues 1-192 of ErbB2 extracellular domain

Template:ABSTRACT PUBMED 21680730

About this Structure

3h3b is a 4 chain structure with sequence from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Zhou H, Zha Z, Liu Y, Zhang H, Zhu J, Hu S, Shen G, Cheng L, Niu L, Greene MI, Teng M, Liu J. Structural Insights into the Down-regulation of Overexpressed p185her2/neu Protein of Transformed Cells by the Antibody chA21. J Biol Chem. 2011 Sep 9;286(36):31676-83. Epub 2011 Jun 16. PMID:21680730 doi:10.1074/jbc.M111.235184

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