2wzj

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Template:STRUCTURE 2wzj

CATALYTIC AND UBA DOMAIN OF KINASE MARK2/(PAR-1) K82R, T208E DOUBLE MUTANT

Template:ABSTRACT PUBMED 20071654

About this Structure

2wzj is a 6 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Marx A, Nugoor C, Panneerselvam S, Mandelkow E. Structure and function of polarity-inducing kinase family MARK/Par-1 within the branch of AMPK/Snf1-related kinases. FASEB J. 2010 Jun;24(6):1637-48. Epub 2010 Jan 13. PMID:20071654 doi:10.1096/fj.09-148064
  • Panneerselvam S, Marx A, Mandelkow EM, Mandelkow E. Structure of the catalytic and ubiquitin-associated domains of the protein kinase MARK/Par-1. Structure. 2006 Feb;14(2):173-83. PMID:16472737 doi:10.1016/j.str.2005.09.022
  • Marx A, Nugoor C, Muller J, Panneerselvam S, Timm T, Bilang M, Mylonas E, Svergun DI, Mandelkow EM, Mandelkow E. Structural variations in the catalytic and ubiquitin-associated domains of microtubule-associated protein/microtubule affinity regulating kinase (MARK) 1 and MARK2. J Biol Chem. 2006 Sep 15;281(37):27586-99. Epub 2006 Jun 27. PMID:16803889 doi:10.1074/jbc.M604865200

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