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2xhx
From Proteopedia
STRUCTURE OF HSP90 WITH SMALL MOLECULE INHIBITOR BOUND
Template:ABSTRACT PUBMED 20718493
About this Structure
2XHX is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Murray CW, Carr MG, Callaghan O, Chessari G, Congreve M, Cowan S, Coyle JE, Downham R, Figueroa E, Frederickson M, Graham B, McMenamin R, O'Brien MA, Patel S, Phillips TR, Williams G, Woodhead AJ, Woolford AJ. Fragment-based drug discovery applied to hsp90. Discovery of two lead series with high ligand efficiency. J Med Chem. 2010 Aug 26;53(16):5942-55. PMID:20718493 doi:10.1021/jm100059d
Page seeded by OCA on Wed Sep 1 09:46:05 2010
Categories: Homo sapiens | Callaghan, O. | Carr, M G. | Chessari, G. | Congreve, M. | Cowan, S. | Coyle, J E. | Downham, R. | Figueroa, E. | Frederickson, M. | Graham, B. | Mcmenamin, R. | Murray, C W. | Obrien, M A. | Patel, S. | Phillips, T R. | Williams, G. | Woodhead, A J. | Woolford, A J.A. | Atp binding domain | Chaperone | Hsp90 | N-terminal domain | Stress response
