3nkx

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Image:3nkx.jpg

Template:STRUCTURE 3nkx

Impaired binding of 14-3-3 to Raf1 is linked to Noonan and LEOPARD syndrome

Template:ABSTRACT PUBMED 20679480

About this Structure

3NKX is a 4 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Molzan M, Schumacher B, Ottmann C, Baljuls A, Polzien L, Weyand M, Thiel P, Rose R, Rose M, Kuhenne P, Kaiser M, Rapp UR, Kuhlmann J, Ottmann C. Impaired binding of 14-3-3 to C-RAF in Noonan Syndrome implies new approaches in diseases with increased Ras signaling. Mol Cell Biol. 2010 Aug 2. PMID:20679480 doi:10.1128/MCB.01636-09

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