3mpk

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Template:STRUCTURE 3mpk

Contents

Crystal Structure of Bordetella pertussis BvgS periplasmic VFT2 domain

Template:ABSTRACT PUBMED 20855615

Function

[BVGS_BORPE] Member of the two-component regulatory system BvgS/BvgA. Phosphorylates BvgA via a four-step phosphorelay in response to environmental signals.

About this Structure

3mpk is a 1 chain structure with sequence from Bordetella pertussis. Full crystallographic information is available from OCA.

Reference

  • Herrou J, Bompard C, Wintjens R, Dupre E, Willery E, Villeret V, Locht C, Antoine R, Jacob-Dubuisson F. Periplasmic domain of the sensor-kinase BvgS reveals a new paradigm for the Venus flytrap mechanism. Proc Natl Acad Sci U S A. 2010 Sep 20. PMID:20855615 doi:10.1073/pnas.1006267107
  • Sinha Roy R, Soni S, Harfouche R, Vasudevan PR, Holmes O, de Jonge H, Rowe A, Paraskar A, Hentschel DM, Chirgadze D, Blundell TL, Gherardi E, Mashelkar RA, Sengupta S. Coupling growth-factor engineering with nanotechnology for therapeutic angiogenesis. Proc Natl Acad Sci U S A. 2010 Aug 3;107(31):13608-13. Epub 2010 Jul 16. PMID:20639469

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