3m5n

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Image:3m5n.png

Template:STRUCTURE 3m5n

Crystal structure of HCV NS3/4A protease in complex with N-terminal product 4B5A

Template:ABSTRACT PUBMED 21084633

About this Structure

3M5N is a 7 chains structure with sequences from Hepatitis c virus subtype 1a. Full crystallographic information is available from OCA.

Reference

  • Romano KP, Ali A, Royer WE, Schiffer CA. Drug resistance against HCV NS3/4A inhibitors is defined by the balance of substrate recognition versus inhibitor binding. Proc Natl Acad Sci U S A. 2010 Dec 7;107(49):20986-91. Epub 2010 Nov 17. PMID:21084633 doi:10.1073/pnas.1006370107

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