This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


TolB

From Proteopedia

Revision as of 16:07, 5 December 2010 by Laura McCauley (Talk | contribs)
Jump to: navigation, search

Template:STRUCTURE 1c5k


Contents

Structure

TolB is a 44-kDa periplasmic protein associated with the outer membrane. It has two domains: an N-terminal α/β domain and a C-terminal six-bladed β-propeller (to which Pal and Colicin E9 bind) [1].

When Pal binds to TolB, several loops and propeller β-strands move, resulting in the latch strand of the β-propeller to move away.

Function

Related Tol entries


References

  1. ↑ Bonsor DA, Hecht O, Vankemmelbeke M, Sharma A, Krachler AM, Housden NG, Lilly KJ, James R, Moore GR, Kleanthous C. Allosteric beta-propeller signalling in TolB and its manipulation by translocating colicins. EMBO J. 2009 Sep 16;28(18):2846-57. Epub 2009 Aug 20. PMID:19696740 doi:10.1038/emboj.2009.224

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Laura McCauley, Joel L. Sussman

Retrieved from "http://52.214.119.220/wiki/index.php/TolB"
Personal tools