3pjc

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Image:3pjc.jpg

Template:STRUCTURE 3pjc

Crystal structure of JAK3 complexed with a potent ATP site inhibitor showing high selectivity within the Janus kinase family

Template:ABSTRACT PUBMED 21155605

About this Structure

3pjc is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Thoma G, Nuninger F, Falchetto R, Hermes E, Tavares GA, Vangrevelinghe E, Zerwes HG. Identification of a Potent Janus Kinase 3 Inhibitor with High Selectivity within the Janus Kinase Family. J Med Chem. 2010 Dec 14. PMID:21155605 doi:10.1021/jm101157q

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