3ovz

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Image:3ovz.jpg

Template:STRUCTURE 3ovz

Cathepsin K in complex with a covalent inhibitor with a ketoamide warhead

Template:ABSTRACT PUBMED 21030256

About this Structure

3OVZ is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Cai J, Robinson J, Belshaw S, Everett K, Fradera X, van Zeeland M, van Berkom L, van Rijnsbergen P, Popplestone L, Baugh M, Dempster M, Bruin J, Hamilton W, Kinghorn E, Westwood P, Kerr J, Rankovic Z, Arbuckle W, Bennett DJ, Jones PS, Long C, Martin I, Uitdehaag JC, Meulemans T. Trifluoromethylphenyl as P2 for ketoamide-based cathepsin S inhibitors. Bioorg Med Chem Lett. 2010 Dec 1;20(23):6890-4. Epub 2010 Oct 26. PMID:21030256 doi:10.1016/j.bmcl.2010.10.012

Page seeded by OCA on Wed Dec 22 09:57:57 2010

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