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Avidin

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Image:1ave1.png

Crystal Structure of Chicken Apo-Avidin, 1ave

Template:STRUCTURE 1ave 3D Structure of Avidin

Avidin (Av) is a protein found in egg white which binds biotin (vitamin B7) with high affinity. This property makes it a powerful tool in various protein pull-down assays. Similar proteins are strepavidin (StrAv) from the bacterium Streptomyces avidinii, Rhizavidin (RhiAv) from Rhizobium etli, Xenavidin from frog, and the avidin-related proteins AVR2 and AVR4. The N-acetylglucosamine sugars are shown as space filling objects in the image on the left.

1 Avidin
2 Strepavidin
3 Rhizavidin
4 Xenavidin
5 Tamavidin
6 AVR2
7 AVR4

Avidin

3fdc, 2jgs, 2c4i, 1vyo, 1rav, 1ave – cAv – chicken
2a5b, 2a5c, 2a8g – cAv+deoxyribose
1nqn, 2cam – cAv (mutant)
1ldo, 1ldq, 1lel, 1ij8, 1avd, 2avi – cAV + biotin derivative

Strepavidin

2bc3, 2iza, 2izb, 2izc, 2izd, 2ize, 2rta, 2rtb, 2rtc - StrAv
1rxh – StrAv (mutant)+ biotinyl p-nitroaniline – Streptomyces avidinii
1rxj, 1rxk, 1nqm, 1kff, 1kl4, 1luq, 1mm9, 1moy, 1n4j, 1n7y, 1n9y, 1nbx, 1swf, 1swu, 3mm0 - StrAv (mutant)
1kl3, 1kl5 - StrAv (mutant) + strep-tag II peptide
1rst, 1rsu - StrAv + strep-tag II peptide
1df8, 1mep, 1n43, 1n9m, 1ndj, 1swg - StrAv (mutant)+biotin
1nc9 - StrAv (mutant)+iminobiotin
2izl, 2rtl, 2rtm, 2rtn, 2rto, 2rtp, 2rtq, 2rtr - StrAv +iminobiotin
1mk5, 1swd, 1swe, 2f01, 2gh7 - StrAv core+biotin
1swa, 1swb, 1swc - StrAv core
1swh, 1swj, 1swl, 1swo, 1swq, 1sws - StrAv core (mutant)
1swk, 1swn, 1swp, 1swr, 1swt, 3mg5 - StrAv core (mutant) + biotin
1stp, 2izf, 2izg, 2izh, 2izi, 2izj, 2rtd, 2rte, 2rtf, 2rtg - StrAv +biotin 1hqq, 1hxl – StrAv + MP-2 (mutant)
1hy2 - StrAv + MP-1
1hxz - StrAv + MP-2
1pts, 1sld, 1sle, 1slg, 1str, 1sts, 1vwa, 1vwb, 1vwc, 1vwd, 1vwe, 1vwf, 1vwg, 1vwh, 1vwi, 1vwj, 1vwk, 1vwl, 1vwm, 1vwn, 1vwo, 1vwp, 1vwq, 1vwr, 2g5l - StrAv + peptide
1slf - StrAv + SO4
1sre, 1srf, 1srg, 1srh, 1sri, 1srj - StrAv + benzoic acid ligands
1lcv, 1lcw, 1lcz, 1i9h – StrAv+biotin derivative
2izk, 2rth, 2rti, 2rtj, 2rtk – StrAV+glycouril
2qcb, 2wpu – StrAv+Ru ligand

Rhizavidin

3ew1 – RhiAv – Rhizobium etli
3ew2 – RhiAV+biotin

Xenavidin

2uz2, 2uyw – XenAv – frog

Tamavidin

2zsc – TanAv – Tamogitake mushroom

AVR2

1wbi – cAVR2

AVR4

2fhl – cAVR4+biotinyl p-nitroaniline
2of9, 2ofa, 1y53 - cAVR4 (mutant)
2fhn, 2of8 - cAVR4 (mutant)+biotinyl p-nitroaniline
1y52, 1y55 - cAVR4 (mutant)+biotin