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3c1k

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Image:3c1k.png

Template:STRUCTURE 3c1k

Contents

Crystal structure of thrombin in complex with inhibitor 15

Template:ABSTRACT PUBMED 18291642

About this Structure

3c1k is a 2 chain structure of Hirudin and Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Isaacs RC, Solinsky MG, Cutrona KJ, Newton CL, Naylor-Olsen AM, McMasters DR, Krueger JA, Lewis SD, Lucas BJ, Kuo LC, Yan Y, Lynch JJ, Lyle EA. Structure-based design of novel groups for use in the P1 position of thrombin inhibitor scaffolds. Part 2: N-acetamidoimidazoles. Bioorg Med Chem Lett. 2008 Mar 15;18(6):2062-6. Epub 2008 Jan 30. PMID:18291642 doi:10.1016/j.bmcl.2008.01.098

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