3ben

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Image:3ben.png

Template:STRUCTURE 3ben

Contents

Structure of N-(12-imidazolyl-dodecanoyl)-L-leucine inhibitor bound to the heme domain of Cytochrome P450-BM3

Template:ABSTRACT PUBMED 18298086

About this Structure

3ben is a 2 chain structure of Cytochrome P450 with sequence from Bacillus megaterium. Full crystallographic information is available from OCA.

See Also

Reference

  • Haines DC, Chen B, Tomchick DR, Bondlela M, Hegde A, Machius M, Peterson JA. Crystal structure of inhibitor-bound P450BM-3 reveals open conformation of substrate access channel. Biochemistry. 2008 Mar 25;47(12):3662-70. Epub 2008 Feb 26. PMID:18298086 doi:10.1021/bi7023964
  • Haines DC, Tomchick DR, Machius M, Peterson JA. Pivotal role of water in the mechanism of P450BM-3. Biochemistry. 2001 Nov 13;40(45):13456-65. PMID:11695892
  • Noble MA, Quaroni L, Chumanov GD, Turner KL, Chapman SK, Hanzlik RP, Munro AW. Imidazolyl carboxylic acids as mechanistic probes of flavocytochrome P-450 BM3. Biochemistry. 1998 Nov 10;37(45):15799-807. PMID:9843385 doi:10.1021/bi980462d

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