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3hhm
From Proteopedia
Contents |
Crystal structure of p110alpha H1047R mutant in complex with niSH2 of p85alpha and the drug wortmannin
Template:ABSTRACT PUBMED 19805105
About this Structure
3hhm is a 2 chain structure of Phosphoinositide 3-Kinases with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Mandelker D, Gabelli SB, Schmidt-Kittler O, Zhu J, Cheong I, Huang CH, Kinzler KW, Vogelstein B, Amzel LM. A frequent kinase domain mutation that changes the interaction between PI3Kalpha and the membrane. Proc Natl Acad Sci U S A. 2009 Oct 6;106(40):16996-7001. Epub 2009 Sep 23. PMID:19805105
Categories: Homo sapiens | Phosphatidylinositol-4,5-bisphosphate 3-kinase | Amzel, L M. | Gabelli, S B. | Mandelker, D. | Vogelstein, B. | 5-triphosphate | Atp-binding | Disease mutation | H1047r | Kinase | Nucleotide-binding | Oncogene | P110 | P85 | Phosphatidilynositol 3 | Pi3k | Pi3kca | Pik3r1 | Polymorphism | Transferase | Transferase/oncoprotein complex | Wortmannin
