3hp2

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Image:3hp2.png

Template:STRUCTURE 3hp2

Contents

Crystal Structure of Human p38alpha complexed with a pyridinone compound

Template:ABSTRACT PUBMED 19751974

About this Structure

3hp2 is a 1 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Selness SR, Devraj RV, Monahan JB, Boehm TL, Walker JK, Devadas B, Durley RC, Kurumbail R, Shieh H, Xing L, Hepperle M, Rucker PV, Jerome KD, Benson AG, Marrufo LD, Madsen HM, Hitchcock J, Owen TJ, Christie L, Promo MA, Hickory BS, Alvira E, Naing W, Blevis-Bal R. Discovery of N-substituted pyridinones as potent and selective inhibitors of p38 kinase. Bioorg Med Chem Lett. 2009 Oct 15;19(20):5851-6. Epub 2009 Aug 27. PMID:19751974 doi:10.1016/j.bmcl.2009.08.082

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