TolQ

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TolQ is a polytopic protein located in the inner (cytoplasmic) membrane. [1] It contains approximately 230 amino acids and is important in the maintenance of the bacterial envelope integrity as well as the import of filamentous bacteriophage and group A colicins. [2]

Structure

There are three membrane spanning segments in TolQ. TM1 is connected to TM2 via a large cytoplasmic loop, with the N-terminal ending in the periplasm.

To view related Tol entries see:

References

  1. ↑ Vianney A, Lewin TM, Beyer WF Jr, Lazzaroni JC, Portalier R, Webster RE. Membrane topology and mutational analysis of the TolQ protein of Escherichia coli required for the uptake of macromolecules and cell envelope integrity. J Bacteriol. 1994 Feb;176(3):822-9. PMID:8300535
  2. ↑ Vianney A, Lewin TM, Beyer WF Jr, Lazzaroni JC, Portalier R, Webster RE. Membrane topology and mutational analysis of the TolQ protein of Escherichia coli required for the uptake of macromolecules and cell envelope integrity. J Bacteriol. 1994 Feb;176(3):822-9. PMID:8300535

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