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Thermolysin

Thermolysin is a protein that is isolated from the thermophile Bacillus thermoproteolyticus"". ^[1] This protein is characterized by a remarkable stability under heat and protein denaturants. ^[2] The structure does not contain any stabilizing disulfide bonds.^[3] Instead, Thermolysin binds four calcium ions that are necessary for its thermal stability. ^[4] Ellen

spinqualitylabelsall models PDB ID 1q8k Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image
1q8k, 15 NMR models ()
Gene:	EIF2S1 OR EIF2A (Homo sapiens)
Structural annotation: Resources: CATH : 1Q8Ka02, 1Q8Ka01, 1Q8Ka03 InterPro : Ipr011488, Ipr003029, Ipr012340 Pfam : PF00575, PF07541 SCOP : d1q8ka1, d1q8ka2 UniProt : P05198
Functional annotation: Cellular component: cytoplasm polysome nucleus eukaryotic translation initiation factor 2 complex eukaryotic translation initiation factor 2B complex Biological process: translation regulation of translational initiation in response to stress regulation of translation Molecular function: RNA binding protein binding translation initiation factor activity
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, RCSB, PDBsum
Coordinates:	save as pdb, mmCIF, xml

Works Cited

1. ↑ Matthews. (1988).
2. ↑ Vita et al., (1985).
3. ↑ Fontana et al., (1977).
4. ↑ Matthews. (1988).