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Please do NOT make changes to this Sandbox. Sandboxes 30-60 are reserved for use by Biochemistry 410 & 412 at Messiah College taught by Dr. Hannah Tims during Fall 2012 and Spring 2013.

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Ouabain

is a cardiac glycoside that inhibits the ATP-dependent sodium-potassium exchange across cell membranes. The binding of ouabain to the sodium-potassium pump prevents the conformational changes necessary for its function. This affects intracellular ion composition in various ways, depending on the cell and the dosage. The compound has therefore been utilized in medicine, both as a drug and in research related to active membrane transport. Its has also been proven effective for original use; as a poison.