3f6u
From Proteopedia
Crystal structure of human Activated Protein C (APC) complexed with PPACK
Template:ABSTRACT PUBMED 12029084
About this Structure
3f6u is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Schmidt AE, Padmanabhan K, Underwood MC, Bode W, Mather T, Bajaj SP. Thermodynamic linkage between the S1 site, the Na+ site, and the Ca2+ site in the protease domain of human activated protein C (APC). Sodium ion in the APC crystal structure is coordinated to four carbonyl groups from two separate loops. J Biol Chem. 2002 Aug 9;277(32):28987-95. Epub 2002 May 23. PMID:12029084 doi:10.1074/jbc.M201892200
- Mather T, Oganessyan V, Hof P, Huber R, Foundling S, Esmon C, Bode W. The 2.8 A crystal structure of Gla-domainless activated protein C. EMBO J. 1996 Dec 16;15(24):6822-31. PMID:9003757
Categories: Homo sapiens | Bajaj, S P. | Bode, W. | Mather, T. | Padmanabhan, K. | Schmidt, A E. | Underwood, M C. | Cleavage on pair of basic residue | Disease mutation | Egf-like domain | Gamma-carboxyglutamic acid | Glycoprotein | Hydrolase | Hydroxylation | Plasma calcium binding | Polymorphism | Protease | Re-refinement | Revised version of the coordinate file pdb 1aut | Serine protease | Thrombophilia | Zymogen
