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2qel

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Template:STRUCTURE 2qel

Crystal structure of the highly amyloidogenic transthyretin mutant TTR G53S/E54D/L55S- heated protein

Template:ABSTRACT PUBMED 17671371

About this Structure

2qel is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Karlsson A, Sauer-Eriksson AE. Heating of proteins as a means of improving crystallization: a successful case study on a highly amyloidogenic triple mutant of human transthyretin. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Aug 1;63(Pt, 8):695-700. Epub 2007 Jul 21. PMID:17671371 doi:10.1107/S1744309107033957
  • Eneqvist T, Andersson K, Olofsson A, Lundgren E, Sauer-Eriksson AE. The beta-slip: a novel concept in transthyretin amyloidosis. Mol Cell. 2000 Nov;6(5):1207-18. PMID:11106758
  • Hornberg A, Eneqvist T, Olofsson A, Lundgren E, Sauer-Eriksson AE. A comparative analysis of 23 structures of the amyloidogenic protein transthyretin. J Mol Biol. 2000 Sep 22;302(3):649-69. PMID:10986125 doi:10.1006/jmbi.2000.4078

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