2q58

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Image:2q58.png

Template:STRUCTURE 2q58

Cryptosporidium parvum putative polyprenyl pyrophosphate synthase (cgd4_2550) in complex with zoledronate

Template:ABSTRACT PUBMED 19101474

About this Structure

2q58 is a 2 chain structure with sequence from Cryptosporidium parvum. This structure supersedes the now removed PDB entry 2her. Full crystallographic information is available from OCA.

Reference

  • Artz JD, Dunford JE, Arrowood MJ, Dong A, Chruszcz M, Kavanagh KL, Minor W, Russell RG, Ebetino FH, Oppermann U, Hui R. Targeting a uniquely nonspecific prenyl synthase with bisphosphonates to combat cryptosporidiosis. Chem Biol. 2008 Dec 22;15(12):1296-306. PMID:19101474 doi:http://dx.doi.org/10.1016/j.chembiol.2008.10.017
  • Vedadi M, Lew J, Artz J, Amani M, Zhao Y, Dong A, Wasney GA, Gao M, Hills T, Brokx S, Qiu W, Sharma S, Diassiti A, Alam Z, Melone M, Mulichak A, Wernimont A, Bray J, Loppnau P, Plotnikova O, Newberry K, Sundararajan E, Houston S, Walker J, Tempel W, Bochkarev A, Kozieradzki I, Edwards A, Arrowsmith C, Roos D, Kain K, Hui R. Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms. Mol Biochem Parasitol. 2007 Jan;151(1):100-10. Epub 2006 Nov 13. PMID:17125854 doi:http://dx.doi.org/10.1016/j.molbiopara.2006.10.011

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