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1h3h

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Image:1h3h.png

Template:STRUCTURE 1h3h

STRUCTURAL BASIS FOR SPECIFIC RECOGNITION OF AN RXXK-CONTAINING SLP-76 PEPTIDE BY THE GADS C-TERMINAL SH3 DOMAIN

Template:ABSTRACT PUBMED 12620234

About this Structure

1h3h is a 2 chain structure with sequence from Homo sapiens and Mus musculus. Full experimental information is available from OCA.

Reference

  • Liu Q, Berry D, Nash P, Pawson T, McGlade CJ, Li SS. Structural basis for specific binding of the Gads SH3 domain to an RxxK motif-containing SLP-76 peptide: a novel mode of peptide recognition. Mol Cell. 2003 Feb;11(2):471-81. PMID:12620234
  • Berry DM, Nash P, Liu SK, Pawson T, McGlade CJ. A high-affinity Arg-X-X-Lys SH3 binding motif confers specificity for the interaction between Gads and SLP-76 in T cell signaling. Curr Biol. 2002 Aug 6;12(15):1336-41. PMID:12176364

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OCA

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