2wad
From Proteopedia
PENICILLIN-BINDING PROTEIN 2B (PBP-2B) FROM STREPTOCOCCUS PNEUMONIAE (STRAIN 5204)
Template:ABSTRACT PUBMED 19233207
About this Structure
2wad is a 3 chain structure with sequence from Streptococcus pneumoniae. Full crystallographic information is available from OCA.
Reference
- Contreras-Martel C, Dahout-Gonzalez C, Martins Ados S, Kotnik M, Dessen A. PBP active site flexibility as the key mechanism for beta-lactam resistance in pneumococci. J Mol Biol. 2009 Apr 10;387(4):899-909. Epub 2009 Feb 20. PMID:19233207 doi:10.1016/j.jmb.2009.02.024
- Pagliero E, Chesnel L, Hopkins J, Croize J, Dideberg O, Vernet T, Di Guilmi AM. Biochemical characterization of Streptococcus pneumoniae penicillin-binding protein 2b and its implication in beta-lactam resistance. Antimicrob Agents Chemother. 2004 May;48(5):1848-55. PMID:15105143
Categories: Streptococcus pneumoniae | Contreras-Martel, C. | Dahout-Gonzalez, C. | Dessen, A. | Dos-Santos-Martins, A. | Kotnik, M. | Antibiotic | Antibiotic resistance | Cell membrane | Cell shape | Cell wall biogenesis/degradation | Infection | Membrane | Penicillin-binding protein | Peptide binding protein | Peptidoglycan | Peptidoglycan synthesis | Resistance | Transmembrane
