3cv9

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Template:STRUCTURE 3cv9

Contents 1 Crystal structure of vitamin D hydroxylase cytochrome P450 105A1 (R73A/R84A mutant) in complex with 1alpha,25-dihydroxyvitamin D3 2 About this Structure 3 See Also 4 Reference

Crystal structure of vitamin D hydroxylase cytochrome P450 105A1 (R73A/R84A mutant) in complex with 1alpha,25-dihydroxyvitamin D3

Template:ABSTRACT PUBMED 18937506

About this Structure

3cv9 is a 1 chain structure of Cytochrome P450 with sequence from Streptomyces griseolus. Full crystallographic information is available from OCA.

See Also

• Cytochrome P450

Reference

• Hayashi K, Sugimoto H, Shinkyo R, Yamada M, Ikeda S, Ikushiro S, Kamakura M, Shiro Y, Sakaki T. Structure-Based Design of a Highly Active Vitamin D Hydroxylase from Streptomyces griseolus CYP105A1. Biochemistry. 2008 Oct 21. PMID:18937506 doi:10.1021/bi801222d
• Sugimoto H, Shinkyo R, Hayashi K, Yoneda S, Yamada M, Kamakura M, Ikushiro S, Shiro Y, Sakaki T. Crystal Structure of CYP105A1 (P450SU-1) in Complex with 1alpha,25-Dihydroxyvitamin D3(,). Biochemistry. 2008 Apr 1;47(13):4017-27. Epub 2008 Mar 4. PMID:18314962 doi:http://dx.doi.org/10.1021/bi7023767
• Hayashi K, Yasuda K, Sugimoto H, Ikushiro S, Kamakura M, Kittaka A, Horst RL, Chen TC, Ohta M, Shiro Y, Sakaki T. Three-step hydroxylation of vitamin D3 by a genetically engineered CYP105A1: enzymes and catalysis. FEBS J. 2010 Oct;277(19):3999-4009. doi: 10.1111/j.1742-4658.2010.07791.x., Epub 2010 Aug 20. PMID:20731719 doi:10.1111/j.1742-4658.2010.07791.x