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3npz

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Template:STRUCTURE 3npz

Contents

Prolactin Receptor (PRLR) Complexed with the Natural Hormone (PRL)

Template:ABSTRACT PUBMED 20875426

Function

[PRL_HUMAN] Prolactin acts primarily on the mammary gland by promoting lactation. [PRLR_RAT] This is a receptor for the anterior pituitary hormone prolactin.

About this Structure

3npz is a 3 chain structure with sequence from Homo sapiens and Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • van Agthoven J, Zhang C, Tallet E, Raynal B, Hoos S, Baron B, England P, Goffin V, Broutin I. Structural Characterization of the Stem-Stem Dimerization Interface between Prolactin Receptor Chains Complexed with the Natural Hormone. J Mol Biol. 2010 Sep 25. PMID:20875426 doi:10.1016/j.jmb.2010.09.036

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