3o0u

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Image:3o0u.png

Template:STRUCTURE 3o0u

Contents

Cathepsin K covalently bound to a cyano-pyrimidine inhibitor with improved selectivity over hERG

Template:ABSTRACT PUBMED 20843687

About this Structure

3o0u is a 1 chain structure of Cathepsin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Rankovic Z, Cai J, Kerr J, Fradera X, Robinson J, Mistry A, Finlay W, McGarry G, Andrews F, Caulfield W, Cumming I, Dempster M, Waller J, Arbuckle W, Anderson M, Martin I, Mitchell A, Long C, Baugh M, Westwood P, Kinghorn E, Jones P, Uitdehaag JC, van Zeeland M, Potin D, Saniere L, Fouquet A, Chevallier F, Deronzier H, Dorleans C, Nicolai E. Optimisation of 2-cyano-pyrimidine inhibitors of cathepsin K: Improving selectivity over hERG. Bioorg Med Chem Lett. 2010 Aug 24. PMID:20843687 doi:10.1016/j.bmcl.2010.08.101

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