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3qkd

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Image:3qkd.png

Template:STRUCTURE 3qkd

Contents

Crystal structure of Bcl-xL in complex with a Quinazoline sulfonamide inhibitor

Template:ABSTRACT PUBMED 21366295

About this Structure

3qkd is a 2 chain structure of Bcl-2 with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Sleebs BE, Czabotar PE, Fairbrother WJ, Fairlie WD, Flygare JA, Huang DC, Kersten WJ, Koehler MF, Lessene G, Lowes K, Parisot JP, Smith BJ, Smith ML, Souers AJ, Street IP, Yang H, Baell JB. Quinazoline sulfonamides as dual binders of the proteins B-cell lymphoma 2 and B-cell lymphoma extra long with potent proapoptotic cell-based activity. J Med Chem. 2011 Mar 24;54(6):1914-26. Epub 2011 Mar 2. PMID:21366295 doi:10.1021/jm101596e

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OCA

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