2y4i

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Template:STRUCTURE 2y4i

Contents 1 KSR2-MEK1 HETERODIMER 2 About this Structure 3 See Also 4 Reference

KSR2-MEK1 HETERODIMER

Template:ABSTRACT PUBMED 21441910

About this Structure

2y4i is a 2 chain structure of Mitogen-activated protein kinase and Mitogen-activated protein kinase kinase with sequence from Homo sapiens and Oryctolagus cuniculus. Full crystallographic information is available from OCA.

See Also

• Mitogen-activated protein kinase
• Mitogen-activated protein kinase kinase

Reference

• Brennan DF, Dar AC, Hertz NT, Chao WC, Burlingame AL, Shokat KM, Barford D. A Raf-induced allosteric transition of KSR stimulates phosphorylation of MEK. Nature. 2011 Apr 21;472(7343):366-9. Epub 2011 Mar 27. PMID:21441910 doi:10.1038/nature09860