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3hbx

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Template:STRUCTURE 3hbx

Contents

Crystal structure of GAD1 from Arabidopsis thaliana

Template:ABSTRACT PUBMED 19580813

Function

[DCE1_ARATH] Catalyzes the production of GABA. The calmodulin-binding is calcium-dependent and it is proposed that this may, directly or indirectly, form a calcium regulated control of GABA biosynthesis.[1]

About this Structure

3hbx is a 6 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA.

Reference

  • Gut H, Dominici P, Pilati S, Astegno A, Petoukhov MV, Svergun DI, Grutter MG, Capitani G. A common structural basis for pH- and calmodulin-mediated regulation in plant glutamate decarboxylase. J Mol Biol. 2009 Sep 18;392(2):334-51. Epub 2009 Jul 4. PMID:19580813 doi:10.1016/j.jmb.2009.06.080
  1. Zik M, Arazi T, Snedden WA, Fromm H. Two isoforms of glutamate decarboxylase in Arabidopsis are regulated by calcium/calmodulin and differ in organ distribution. Plant Mol Biol. 1998 Aug;37(6):967-75. PMID:9700069

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