3poz
From Proteopedia
Contents |
EGFR Kinase domain complexed with tak-285
Template:ABSTRACT PUBMED 21454582
About this Structure
3poz is a 1 chain structure of Epidermal Growth Factor Receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Aertgeerts K, Skene R, Yano J, Sang BC, Zou H, Snell G, Jennings A, Iwamoto K, Habuka N, Hirokawa A, Ishikawa T, Tanaka T, Miki H, Ohta Y, Sogabe S. Structural Analysis of the Mechanism of Inhibition and Allosteric Activation of the Kinase Domain of HER2 Protein. J Biol Chem. 2011 May 27;286(21):18756-65. Epub 2011 Mar 30. PMID:21454582 doi:10.1074/jbc.M110.206193
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Aertgeerts, K. | Skene, R. | Sogabe, S. | Anti-oncogene | Atp-binding | Cell cycle | Disease mutation | Glycoprotein | Kinase domain | Membrane | Nucleotide-binding | Phosphoprotein | Receptor | Secreted | Transferase | Transferase-transferase inhibitor complex | Transmembrane | Tyrosine-protein kinase
