2ydo

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Template:STRUCTURE 2ydo

Contents

THERMOSTABILISED HUMAN A2A RECEPTOR WITH ADENOSINE BOUND

Template:ABSTRACT PUBMED 21593763

Function

[AA2AR_HUMAN] Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

About this Structure

2ydo is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Lebon G, Warne T, Edwards PC, Bennett K, Langmead CJ, Leslie AG, Tate CG. Agonist-bound adenosine A(2A) receptor structures reveal common features of GPCR activation. Nature. 2011 May 18. PMID:21593763 doi:10.1038/nature10136
  • Lebon G, Bennett K, Jazayeri A, Tate CG. Thermostabilisation of an Agonist-Bound Conformation of the Human Adenosine A(2A) Receptor. J Mol Biol. 2011 Apr 9. PMID:21501622 doi:10.1016/j.jmb.2011.03.075

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