This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


426d

From Proteopedia

Revision as of 17:12, 21 February 2008 by OCA (Talk | contribs)
Jump to: navigation, search
Image:426d.gif

426d, resolution 3.0Å

Drag the structure with the mouse to rotate

THE STRUCTURE OF MOST STUDIED DNA FRAGMENT CHANGES UNDER THE INFLUENCE OF IONS: A NEW PACKING OF D(CGCGAATTCGCG)

Overview

The title oligonucleotide and many related dodecamers have been extensively studied alone and as DNA-drug complexes. In practically all cases they were found to crystallize in the same space group, stabilized by interactions among the terminal guanine bases. Here we report new packing interactions (R3) in the presence of Ca2+. The oligonucleotides interact by placing their terminal guanines in the narrow groove of a neighbor molecule, an interaction which had never been found in dodecamers.

About this Structure

426D is a Protein complex structure of sequences from [1] with as ligand. Full crystallographic information is available from OCA.

Reference

The structure of the most studied DNA fragment changes under the influence of ions: a new packing of d(CGCGAATTCGCG)., Liu J, Malinina L, Huynh-Dinh T, Subirana JA, FEBS Lett. 1998 Nov 6;438(3):211-4. PMID:9827547

Page seeded by OCA on Thu Feb 21 19:12:13 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/426d"
Personal tools