3rqd

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Template:STRUCTURE 3rqd

Contents 1 Ideal Thiolate-Zinc Coordination Geometry in Depsipeptide Binding to Histone Deacetylase 8 2 About this Structure 3 See Also 4 Reference

Ideal Thiolate-Zinc Coordination Geometry in Depsipeptide Binding to Histone Deacetylase 8

Template:ABSTRACT PUBMED 21790156

About this Structure

3rqd is a 4 chain structure of Histone deacetylase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Histone deacetylase

Reference

• Cole KE, Dowling DP, Boone MA, Phillips AJ, Christianson DW. Structural basis of the antiproliferative activity of largazole, a depsipeptide inhibitor of the histone deacetylases. J Am Chem Soc. 2011 Aug 17;133(32):12474-7. Epub 2011 Jul 26. PMID:21790156 doi:10.1021/ja205972n