User:Robert Dutnall/Sandbox 1 alpha helix

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Biochemistry Tutorial #2 - Secondary Structure

Blah, blah, blah

Note: in these tutorials, the images are 3D interactive images. You can manipulate them as you wish to get a better view of the molecules.

You can rotate the structure by holding down the right mouse button and dragging.

Other things you can do:

To rotate: left drag
To Zoom: scroll button or shift + left drag
To Translate: ctrl + right drag
Right click to bring up an options menu

An α-helix

This is a 19 amino acid chain in α-helical conformation.

Drag the structure with the mouse to rotate

All the atoms are shown in this initial orientation (C = green; N = blue; O = red; S = yellow; H = white).

Identify the N- and C-termini.

You should be able to see that is helical with a right-handed twist.

Click the "toggle spin" button in the box to stop the structure from rotating.

Now use your mouse to rotate the structure to look down the helix axis. If you have any problems with finding this view, to zoom in and look down the helix axis from the N-terminal end.

The hydrogen bonds connect the backbone NH groups and C=O. The N-H group is the donor, the oxygen in the C=O group is the acceptor (N-H--->O=C). More text here

The atoms of each amino side chain have been colored light blue to show them more clearly.

What is the general orientation of the side chains with respect to the helix axis?

Proteopedia Page Contributors and Editors (what is this?)

Robert Dutnall

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