3tik

From Proteopedia

Unreleased structure

The entry 3tik is ON HOLD until Paper Publication

Authors: Hargrove, T.Y., Wawrzak, Z., Kraus, J.M., Gelb, M.H., Buckner, F.S., Waterman, M.R., Lepesheva, G.I.

Description: Sterol 14-alpha demethylase (CYP51) from Trypanosoma brucei in complex with the tipifarnib derivative 6-((4-chlorophenyl)(methoxy)(1-methyl-1H-imidazol-5-yl)methyl)-4-(2,6-difluorophenyl)-1-methylquinolin-2(1H)-one