3ttz

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Image:3ttz.jpg

Template:STRUCTURE 3ttz

Crystal structure of a topoisomerase ATPase inhibitor

Template:ABSTRACT PUBMED 22041057

About this Structure

3ttz is a 2 chain structure with sequence from Staphylococcus aureus. Full crystallographic information is available from OCA.

Reference

  • Sherer BA, Hull K, Green O, Basarab G, Hauck S, Hill P, Loch JT 3rd, Mullen G, Bist S, Bryant J, Boriack-Sjodin A, Read J, Degrace N, Uria-Nickelsen M, Illingworth RN, Eakin AE. Pyrrolamide DNA gyrase inhibitors: Optimization of antibacterial activity and efficacy. Bioorg Med Chem Lett. 2011 Oct 12. PMID:22041057 doi:10.1016/j.bmcl.2011.10.010

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OCA

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