DNA methyltransferase
From Proteopedia
DNA methyltransferase (DNMT) catalyzes the transfer of methyl group to DNA. DNMT uses S-adenosyl methionine (SAM) as the methyl donor.
Contents |
3D Structures of DNA methyltransferase
Updated November 2011
Methylguanine DNMT
1sfe – O6-methylguanine DNMT C terminal – Escherichia coli
1qnt, 1eh6, 3llr - hO6-methylguanine DNMT – human
1t38 - hO6-methylguanine DNMT (mutant) + DNA
1t39, 1yfh - hO6-methylguanine DNMT + DNA
1eh7 - hO6-methylguanine DNMT methylated
1eh8 - hO6-methylguanine DNMT benzylated
1wrj - O6-methylguanine DNMT - Sulfolobus tokodaii
2g7h - O6-methylguanine DNMT – Methanocaldococcus jannaschii
2kif, 2kim - O6-methylguanine DNMT – Vibrio parahaemolyticus - NMR
Methylcytosine DNMT
2qrv - h-cytosine DNMT
3epz - h-cytosine DNMT replecation foci-targeting sequence
3flg - h-cytosine DNMT ADD domain
3a1a - h-cytosine DNMT PWWP domain
1g55 - h-cytosine DNMT2 (mutant)
3av4, 1khc - m-cytosine DNMT – mouse
2c7o, 2c7p, 2c7q, 2c7r, 3pta – Hh-cytosine DNMT + DNA + S-adenonosyl cysteine
2uyc, 2uyh, 2uz4 - Hh-cytosine DNMT (mutant) + DNA + S-adenonosyl cysteine
3a1b - h-cytosine DNMT ADD domain + histone H3
3pt6, 3pt9 – m-cytosine DNMT + DNA
3av5 - m-cytosine DNMT + S-adenonosyl cysteine
3av6 - m-cytosine DNMT + SAM
3swr - h-cytosine DNMT + sinefungin
1boo - cytosine DNMT (mutant) – Proteus vulgaris
1fjx – HhDNMT (mutant) + DNA + S-adenonosyl cysteine - Haemophilus haemolyticus
1hmy – HhHaeiii DNMT + S-adenonosyl methionine
1m0e - HhDNMT (mutant) + DNA + inhibitor
2i9k - HhDNMT (mutant) + DNA
2hr1 - HhDNMT + DNA + ADOHCY
2z6q, 2z6u, 2zcj - HhDNMT (mutant) + DNA + ADOHCY
1svu - HhDNMT (mutant)
Methyladenine DNMT
1nw5 – RsN6-adenine DNMT + SAM – Rhodobacter sphaeroides
1nw6 - RsN6-adenine DNMT + sinefungin
1nw8 - RsN6-adenine DNMT (mutant)
2ibs, 2ibt, 2ih2, 2ih4, 2ih5, 2np6, 2np7 - adenine DNMT Taqi + DNA + cofactor analog – Thermus aquaticus
1nw7 - RsN6-adenine DNMT + S-adenonosyl cysteine
