3t9i

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Template:STRUCTURE 3t9i

Pim1 complexed with a novel 3,6-disubstituted indole at 2.6 Ang Resolution

Template:ABSTRACT PUBMED 21945284

About this Structure

3t9i is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Nishiguchi GA, Atallah G, Bellamacina C, Burger MT, Ding Y, Feucht PH, Garcia PD, Han W, Klivansky L, Lindvall M. Discovery of novel 3,5-disubstituted indole derivatives as potent inhibitors of Pim-1, Pim-2, and Pim-3 protein kinases. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6366-9. Epub 2011 Sep 10. PMID:21945284 doi:10.1016/j.bmcl.2011.08.105

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