3vhl

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Image:3vhl.jpg

Template:STRUCTURE 3vhl

Crystal structure of the DHR-2 domain of DOCK8 in complex with Cdc42 (T17N mutant)

Template:ABSTRACT PUBMED 22461490

About this Structure

3vhl is a 2 chain structure with sequence from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Harada Y, Tanaka Y, Terasawa M, Pieczyk M, Habiro K, Katakai T, Hanawa-Suetsugu K, Kukimoto-Niino M, Nishizaki T, Shirouzu M, Duan X, Uruno T, Nishikimi A, Sanematsu F, Yokoyama S, Stein JV, Kinashi T, Fukui Y. DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses. Blood. 2012 May 10;119(19):4451-61. Epub 2012 Mar 28. PMID:22461490 doi:10.1182/blood-2012-01-407098

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OCA

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