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3tpz

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Revision as of 06:43, 15 February 2012 by OCA (Talk | contribs)
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Image:3tpz.jpg

Template:STRUCTURE 3tpz

2.1 Angstrom crystal structure of the L114P mutant of E. Coli KsgA

Template:ABSTRACT PUBMED 22142337

About this Structure

3tpz is a 2 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

  • O'Farrell HC, Musayev FN, Scarsdale JN, Rife JP. Control of Substrate Specificity by a Single Active Site Residue of the KsgA Methyltransferase. Biochemistry. 2012 Jan 10;51(1):466-74. Epub 2011 Dec 22. PMID:22142337 doi:10.1021/bi201539j
  • O'Farrell HC, Musayev FN, Scarsdale JN, Rife JP. Binding of adenosine-based ligands to the MjDim1 rRNA methyltransferase: implications for reaction mechanism and drug design. Biochemistry. 2010 Mar 30;49(12):2697-704. PMID:20163168 doi:10.1021/bi901875x
  • Pulicherla N, Pogorzala LA, Xu Z, O Farrell HC, Musayev FN, Scarsdale JN, Sia EA, Culver GM, Rife JP. Structural and functional divergence within the Dim1/KsgA family of rRNA methyltransferases. J Mol Biol. 2009 Sep 4;391(5):884-93. Epub 2009 Jun 9. PMID:19520088 doi:10.1016/j.jmb.2009.06.015
  • O'Farrell HC, Scarsdale JN, Rife JP. Crystal structure of KsgA, a universally conserved rRNA adenine dimethyltransferase in Escherichia coli. J Mol Biol. 2004 May 28;339(2):337-53. PMID:15136037 doi:10.1016/j.jmb.2004.02.068

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